The Drug Discovery & Development Facility is designed to promote the design, discovery and development of new drugs through multi-disciplinary research involving chemistry, medicinal chemistry, pharmaceutics, pharmaceutical technology and biology. The architecture provides facilities for computer-aided drug design, computational pharmaceutics, organic synthesis, molecule purification and characterization as well as in vitro and in vivo biological screening.

• Computer-aided drug design and development
• Target-based / Ligand-based / Cheminformatics-based drug designing
• In-silico ‘Knock-out’ / Mutation studies
• Lead optimization (binding affinity, selectivity, off-target effects, solubility enhancement)
• In-silico formulation development studies

• Chemical synthesis and characterization of novel chemical entities
• API and API intermediate synthesis
• Impurity synthesis (in collaboration with Indian Pharmacopoeia Commission)
• Formulation development of Novel Nanotechnology based Herbal and Nutraceutical Products
• Standardization of herbal extracts, herbal and nutraceutical products (AYUSH products)
• Cell line studies of API, Finished products, Herbal extracts, phytoconstituents

• Anticancer bioassays
• Cytotoxicity assays